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Figure 1 | BMC Cancer

Figure 1

From: The role of hepatocyte nuclear factor 4alpha in metastatic tumor formation of hepatocellular carcinoma and its close relationship with the mesenchymal–epithelial transition markers

Figure 1

The expression of MET marks in primary tumors and their corresponding metastases suggested the occurrence of MET in the metastases. A) The number of the lesions with different staining intensity of the MET marks (including E-cadherin, N-cadherin, Fibronectin and Vimentin) in the primary tumors and their corresponding metastases. B) The expression change of MET marks in the metastases compared with their corresponding primary tumors (increased E-cadherin, decreased N-cadherin, Fibronectin and Vimentin expression), marking via the lines, showed the occurrence of MET in the metastases. C) The examples of the cases with increased E-cadherin, decreased N-cadherin, Fibronectin and Vimentin expression in the metastases compared with their primary tumors were showed. In the normal tumor-adjacent tissue, the expression of E-cadherin was mainly strong, but the expression of N-cadherin, Fibronectin and Vimentin was usually negative.

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