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Table 4 Univariate analysis according to the genotyping of vascular endothelial growth factor

From: The relationship of Vascular endothelial growth factor gene polymorphisms and clinical outcome in advanced gastric cancer patients treated with FOLFOX: VEGF polymorphism in gastric cancer

Genotype Polymorphism No. of patients PFS (Mo) P* OS (Mo) P*
−2578C/A CC 116 4.9 0.676 12.8 0.423
  CA 63 3.9   14.4  
  AA 11 3.0   11.5  
−2489C/T CC 116 4.9 0.249 12.8 0.462
  CT 60 4.0   14.4  
  TT 14 2.9   11.5  
−1498 T/C TT 116 4.9 0.647 12.8 0.440
  TC 61 3.9   13.7  
  CC 13 3.0   11.8  
−634 G/C GG 54 3.5 0.043 13.1 0.407
  GC 93 4.8   14.4  
  CC 43 4.9   11.5  
+936C/T CC 135 4.5 0.925 13.1 0.711
  CT 45 4.7   11.9  
  TT 10 3.9   11.9  
+1612 G/A GG 139 4.4 0.448 12.8 0.644
  GA 47 5.0   14.4  
  AA 4 2.1   10.6  
  1. *by log-rank test.
  2. PFS: progression free survival, Mo: months, OS: overall survival.
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BMC Cancer

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