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Table 3 Response according to genotyping of vascular endothelial growth factor

From: The relationship of Vascular endothelial growth factor gene polymorphisms and clinical outcome in advanced gastric cancer patients treated with FOLFOX: VEGF polymorphism in gastric cancer

Genotype Polymorphism ORR % P*
−2578C/A CC 41/116 35.3 0.798
  CA 20/63 31.7  
  AA 3/11 27.3  
−2489C/T CC 41/116 35.3 0.812
  CT 19/160 31.7  
  TT 4/14 28.6  
−1498 T/C TT 41/116 30.8 0.832
  TC 19/61 31.1  
  CC 4/13 35.3  
−634 G/C GG 12/54 22.2 0.034
  GC 30/93 32.3  
  CC 22/43 51.1  
+936C/T CC 46/135 34.1 0.852
  CT 14/45 31.1  
  TT 4/10 40.0  
+1612 G/A GG 50/139 36.0 0.333
  GA 12/47 25.5  
  AA 2/4 50.0  
  1. *by Fisher’s exact and chi-square test.
  2. ORR: overall response rate.