Table 3 Response according to genotyping of vascular endothelial growth factor
Genotype | Polymorphism | ORR | % | P* |
|---|---|---|---|---|
−2578C/A | CC | 41/116 | 35.3 | 0.798 |
CA | 20/63 | 31.7 | ||
AA | 3/11 | 27.3 | ||
−2489C/T | CC | 41/116 | 35.3 | 0.812 |
CT | 19/160 | 31.7 | ||
TT | 4/14 | 28.6 | ||
−1498 T/C | TT | 41/116 | 30.8 | 0.832 |
TC | 19/61 | 31.1 | ||
CC | 4/13 | 35.3 | ||
−634 G/C | GG | 12/54 | 22.2 | 0.034 |
GC | 30/93 | 32.3 | ||
CC | 22/43 | 51.1 | ||
+936C/T | CC | 46/135 | 34.1 | 0.852 |
CT | 14/45 | 31.1 | ||
TT | 4/10 | 40.0 | ||
+1612 G/A | GG | 50/139 | 36.0 | 0.333 |
GA | 12/47 | 25.5 | ||
AA | 2/4 | 50.0 |