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Figure 1 | BMC Cancer

Figure 1

From: Intestinal-type of differentiation predicts favourable overall survival: confirmatory clinicopathological analysis of 198 periampullary adenocarcinomas of pancreatic, biliary, ampullary and duodenal origin

Figure 1

Histopathological Subtypes of Periampullary Adenocarcinomas. (a-e) hematoxylin-eosin stained tissue (H&E): (a, b) adenocarcinoma of the pancreatobiliary type with simple branching glands lined by cuboidal columnar tumor cells with rounded nuclei and focally cribriform growth pattern. c adenocarcinoma of the mixed type showing both intestinal and pancreatobiliary growth pattern evenly distributed, d adenocarcinoma of the intestinal type with characteristic branching tubular glands, simple and pseudostratified mucin producing glandular epithelium with elongated hyperchromatic and pseudostratified nuclei, (e) poorly differentiated carcinoma displaying solid insular glandular growth pattern and remarkable nuclear atypia; (f-h) typical immunohistochemical staining patterns for cytokeratin 7 (CK7) in a pancreatobiliary type adenocarcinoma (g), cytokeratin 20 (CK20) (f) and caudal type homeobox 2 (CDX2) (h) in an intestinal type adenocarcinoma, pictures taken at 20-fold magnification.

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