Table 1 Specific symptoms in women with malignant or benign ovarian tumors and controls (healthy women)
Malignant | Benign | Controls | p-value | p-value | p-value | ||||
|---|---|---|---|---|---|---|---|---|---|
tumors | tumors | ||||||||
(n = 60) | (n = 116) | (150) | (Malignant vs. benign) | (Malignant vs. controls) | (Benign vs. controls) | ||||
Symptom | N | (%) | n | (%) | n | (%) | |||
Pelvic pain | 30 | (50.0) | 23 | (19.7) | 2 | (1.3) | <0.01 | <0.01 | <0.01 |
Abdominal pain | 23 | (38.3) | 10 | (8.5) | 0 | - | <0.01 | <0.01 | <0.01 |
Back pain | 17 | (28.3) | 10 | (8.6) | 0 | - | <0.01 | <0.01 | <0.01 |
Unable to eat normally | 22 | (36.7) | 8 | (6.8) | 1 | (0.7) | <0.01 | <0.01 | 0.01 |
Feeling full quickly | 22 | (36.1) | 11 | (9.4) | 1 | (0.7) | <0.01 | <0.01 | <0.01 |
Indigestion | 15 | (24.6) | 7 | (6.0) | 1 | (0.7) | <0.01 | <0.01 | 0.02 |
Nausea or vomiting | 11 | (18.0) | 4 | (3.4) | 1 | (0.7) | <0.01 | <0.01 | 0.17 |
Weight loss | 19 | (31.7) | 25 | (21.6) | 11 | (7.3) | 0.19 | <0.01 | <0.01 |
Abdominal bloating | 36 | (60.0) | 32 | (27.4) | 0 | - | <0.01 | <0.01 | <0.01 |
Increased abdomen size | 38 | (63.3) | 31 | (26.7) | 1 | (0.7) | <0.01 | <0.01 | <0.01 |
Able to feel abdominal mass | 14 | (23.3) | 11 | (9.4) | 0 | - | 0.02 | <0.01 | <0.01 |
Urinary urgency | 8 | (13.3) | 8 | (6.8) | 2 | (1.3) | 0.25 | <0.01 | 0.02 |
Frequent urination | 12 | (20.0) | 16 | (13.7) | 2 | (1.3) | 0.38 | <0.01 | <0.01 |
Constipation | 2 | (3.3) | 2 | (1.7) | 0 | - | 0.60 | 0.08 | 0.18 |
Diarrhea | 3 | (5.1) | 1 | (0.9) | 0 | - | 0.11 | 0.02 | 0.43 |
Menstrual irregularities* | 1 | (1.6) | 1 | (0.9) | 1 | (0.7) | 1.0 | 0.49 | 1.0 |
Bleeding after menopause** | 6 | (10.0) | 1 | (0.9) | 0 | - | <0.01 | <0.01 | 0.43 |
Pain during intercourse*** | 0 | - | 0 | - | 1 | (0.7) | NC | 1.0 | 1.0 |
Bleeding with intercourse | 0 | - | 0 | - | 0 | - | NC | NC | NC |
Fatigue | 20 | (33.3) | 16 | (13.7) | 3 | (2.0) | <0.01 | <0.01 | <0.01 |
Leg swelling | 6 | (10.0) | 11 | (9.4) | 1 | (0.7) | 1.0 | <0.01 | <0.01 |
Difficulty breathing | 9 | (15.0) | 5 | (4.3) | 2 | (1.3) | 0.02 | <0.01 | 0.24 |