Skip to main content

Table 2 Results of cox regression analyses 1

From: Prognostic impact of tumor infiltrating CD8+ T cells in association with cell proliferation in ovarian cancer patients - a study of the OVCAD consortium

A) Prognostic values of various parameters on overall survival

N = 197 (93 events)

Univariate

Multivariable

 

HR (CI95%)

p

HR (CI95%)

p

Age (continuous, per decade)

1.35 (1.14-1.60)

<0.001

1.26 (1.07-1.48)

0.006

FIGO (ordinal, per stage)

2.22 (1.44-3.42)

<0.001

2.18 (1.38-3.45)

<0.001

Residual tumor (yes vs. no)

2.01 (1.32-3.06)

0.001

1.87 (1.21-2.88)

0.005

CD8+ cell infiltration (continuous, per doubling)

0.86 (0.77-0.96)

0.006

0.82 (0.73-0.92)

<0.001

Ki67+ tumor cells (<5% vs. ≥5%)

3.27 (1.57-6.83)

0.002

3.34 (1.59-7.04)

0.001

B) Prognostic values of various parameters on progression-free survival

N = 180 (139 events)

Univariate

Multivariable

 

HR (CI95%)

p

HR (CI95%)

p

Age (continuous, per decade)

1.18 (1.03-1.34)

0.016

1.08 (0.94-1.23)

0.268

FIGO (ordinal, per stage)

2.51 (1.72-3.67)

<0.001

2.19 (1.43-3.35)

<0.001

Residual tumor (yes vs. no)

2.07 (1.44-2.98)

<0.001

1.64 (1.11-2.43)

0.013

CD8 cell infiltration (continuous, per doubling)

0.97 (0.89-1.05)

0.447

0.92 (0.84-1.01)

0.074

Ki67 (<5% vs. ≥5%)

1.63 (0.76-3.49)

0.209

1.51 (0.69-3.28)

0.299

  1. 1HR and p values of statistically significant parameters presented in bold.