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Table 4 Characteristics of DMBA-induced tumors in SENCAR mice on different dietary treatment

From: Characterization of synergistic anti-cancer effects of docosahexaenoic acid and curcumin on DMBA-induced mammary tumorigenesis in mice

  Corn oil Corn oil + CCM DHASCO DHASCO + CCM Pvalue
Number of mice developing tumors & 11 (73.3%) 11 (73.3%) 10 (66.7%) 4 (26.7%) 0.024
(n = 15) (n = 15) (n = 15) (n = 15)
Number of tumors/animal # 1.27 ± 1.03 1.20 ± 1.01 0.87 ± 0.74 0.27 ± 0.45 0.036
(n-15) (n = 15) (n = 15) (n = 15)
Tumor weight + (g) 1.1 ± 0.6 1.3 ± 0.8 1.4 ± 0.3 0.3 ± 0.3 0.026
(n = 11) (n = 11) (n = 10) (n = 4)
Time to tumor development * (days) 80 (70, 87) 87 (73, 108) 92 (77, 101) NE (114, NE) 0.018
(n = 15) (n = 15) (n = 15) (n = 15)
  1. & compared between groups using Chi-square test;
  2. + compared between groups using ANOVA;
  3. # compared between groups using one-way ANOVA with Scheffe post hoc test.
  4. * Data summarized median (Q1, Q3) and compared between groups using the log-rank test.
  5. NE not estimable.
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BMC Cancer

ISSN: 1471-2407

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