Characterization of synergistic anti-cancer effects of docosahexaenoic acid and curcumin on DMBA-induced mammary tumorigenesis in mice

Table 4 Characteristics of DMBA-induced tumors in SENCAR mice on different dietary treatment

	Corn oil	Corn oil + CCM	DHASCO	DHASCO + CCM	Pvalue
Number of mice developing tumors ^&	11 (73.3%)	11 (73.3%)	10 (66.7%)	4 (26.7%)	0.024
Number of mice developing tumors ^&	(n = 15)	(n = 15)	(n = 15)	(n = 15)	0.024
Number of tumors/animal ^#	1.27 ± 1.03	1.20 ± 1.01	0.87 ± 0.74	0.27 ± 0.45	0.036
Number of tumors/animal ^#	(n-15)	(n = 15)	(n = 15)	(n = 15)	0.036
Tumor weight ⁺ (g)	1.1 ± 0.6	1.3 ± 0.8	1.4 ± 0.3	0.3 ± 0.3	0.026
Tumor weight ⁺ (g)	(n = 11)	(n = 11)	(n = 10)	(n = 4)	0.026
Time to tumor development ^* (days)	80 (70, 87)	87 (73, 108)	92 (77, 101)	NE (114, NE)	0.018
Time to tumor development ^* (days)	(n = 15)	(n = 15)	(n = 15)	(n = 15)	0.018

& compared between groups using Chi-square test;
+ compared between groups using ANOVA;
# compared between groups using one-way ANOVA with Scheffe post hoc test.
* Data summarized median (Q1, Q3) and compared between groups using the log-rank test.
NE not estimable.

ISSN: 1471-2407