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Table 2 Logrank test (Mantel-Cox)

From: ITGA3 and ITGB4 expression biomarkers estimate the risks of locoregional and hematogenous dissemination of oral squamous cell carcinoma

  Lymph node metastasis Primary site recurrence Distant metastasis OSCC death 7
Gene expression ratio     
High-ITGA3/CD9 0.000 0.005 0.001 0.000
High-ITGB4/JUP 0.022 0.237 0.000 0.001
Clinicopathological parameter  
Age1 0.449 0.321 0.207 0.365
Sex 0.417 0.858 0.149 0.584
Size2 0.000 0.007 0.703 0.084
T3-43 0.000 0.000 0.390 0.092
YK44 0.000 0.018 0.001 0.000
Positive margin5 ------ 0.000 0.427 0.000
Clinical event  
Lymph node metastasis6 ------ 0.001 0.000 0.000
Primary site recurrence ------ ------ 0.840 0.000
Distant metastasis ------ ------ ------ 0.000
  1. Numbers in the table show P-values for the parameters. 1Age was categorized into two groups ≥69 and <69 based on the median age. 2Major width of the tumor was categorized into >30 mm and ≤30 mm. 3 T3 to T4 of tumor (T) category according to the International Union Against Cancer (UICC) TNM classification of malignant tumors of the lip and oral cavity. 44c or 4d of the histopathologic classification of oral squamous cell carcinoma according to Yamamoto et al., 1983 (10). 5Histological tumor positive of the surgical margin. 6Determined by pathologic examination of a surgical specimen. 7Death outcome from oral squamous cell carcinoma. Continuous variables of gene expression ratios are categorized according to the cut off points introduced by receiver operating characteristic curves. Median of ITGA3/CD9 and higher 30% group of ITGB4/JUP are used for categorization.