|
Cell line/treatment
|
Sub-G1
|
G0/G1
|
S
|
G2/M
|
|---|
|
BxPc3
| | | | |
|
Control
|
7.7±1.4
|
55.6±2.3
|
25.4±5
|
10.8±1.8
|
|
NVP-AEW541
|
7.9±2.7
|
69.7±4.5*
|
15.7±2.9
|
6.2±1.1
|
|
AsPC-1
| | | | |
|
Control
|
1±0.02
|
46.1±0.3
|
31.8±0.2
|
19.5±0.1
|
|
NVP-AEW541
|
3.9±0.2*
|
47.1±0.4
|
35.7±1.5
|
14±2.6
|
|
Capan-1
| | | | |
|
Control
|
3.8±0.3
|
50.6±2.5
|
25.5±3.1
|
18.6±1.1
|
|
NVP-AEW541
|
7±0.2*
|
53.6±1.3
|
23±1.8
|
15.1±1.4
|
|
PT45
| | | | |
|
Control
|
2.3±0.6
|
74.4±4.3
|
12.3±2.8
|
10.1±1
|
|
NVP-AEW541
|
10.2±2.7*
|
59.8±1.4*
|
19.7±4.8
|
9.9±2.4
|
|
Miapaca-2
| | | | |
|
Control
|
4.6±2.6
|
76.1±2.2
|
10±1.3
|
8.6±0.5
|
|
NVP-AEW541
|
5.5±2.7
|
81±1.3
|
9.4±0.8
|
4.5±3.7
|
|
PANC1
| | | | |
|
Control
|
5.6±1.5
|
48.3±4.6
|
11.6±0.1
|
32.7±4.7
|
|
NVP-AEW541
|
9.3±0.5
|
72.4±2.1*
|
12.1±0.3
|
4.9±0.4*
|
|
FA6
| | | | |
|
Control
|
13.8±2
|
48.3±3.1
|
25.4±4.8
|
11.2±0.4
|
|
NVP-AEW541
|
36.8±2.8*
|
33.2±1.2*
|
22.2±1.3
|
6.9±2.2
|
- Each population is expressed as percentage of gated cells (mean of three independent experiments ± S.D).* depicts statistically significant difference (p<0.05) compared to control values.
