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Table 4 Odds ratios (95% CI) of mixed/dense mammographic density by screening age, period, and birth cohort

From: Mammographic density in birth cohorts of Danish women: a longitudinal study

Copenhagen

N F/MD*

Crude odds ratio

Adjusted odds ratio

Funen

N F/MD*

Crude odds ratio

Adjusted odds ratio

Age 2

   

Age 2

   

50-51

2169|5649

Ref.

Ref.

50-51

5125|17997

Ref

Ref

52-53

5300|11508

0.87 (0.84-0.90)

0.92 (0.89-0.95)

52-53

6232|16045

0.82 (0.80-0.83)

0.89 (0.86-0.91)

54-55

5548|9414

0.78 (0.76-0.81)

0.89 (0.85-0.92)

54-55

6620|13886

0.74 (0.72-0.76)

0.87 (0.85-0.90)

56-57

5763|7783

0.71 (0.69-0.74)

0.86 (0.82-0.90)

56-57

6749|11790

0.68 (0.66-0.70)

0.88 (0.85-0.91)

58-59

5783|6672

0.67 (0.64-0.69)

0.86 (0.82-0.90)

58-59

6513|10263

0.64 (0.62-0.66)

0.92 (0.89-0.95)

60-61

6015|5992

0.62 (0.60-0.65)

0.85 (0.81-0.90)

60-61

6501|9163

0.60 (0.58-0.62)

0.97 (0.93-1.02)

62-63

6225|5533

0.59 (0.57-0.62)

0.86 (0.82-0.90)

62-63

6519|8215

0.58 (0.56-0.60)

1.05 (1.00-1.10)

64-65

6408|5219

0.55 (0.53-0.58)

0.85 (0.80-0.89)

64-65

6514|7306

0.56 (0.54-0.58)

1.12 (1.07-1.17)

66-67

6685|5201

0.54 (0.52-0.56)

0.86 (0.81-0.91)

66-67

6360|6705

0.56 (0.54-0.58)

1.22 (1.16-1.29)

68-69

6798|5211

0.53 (0.51-0.55)

0.88 (0.83-0.93)

68-69

6183|5979

0.54 (0.52-0.56)

1.30 (1.23-1.37)

70-71

3532|2662

0.50 (0.48-0.53)

0.87 (0.81-0.92)

-

-

-

-

Period 2

   

Period 2

   

1991-1993

15814|14177

Ref.

Ref.

1994-1995

16100|22959

Ref

Ref

1993-1995

13092|12827

0.98 (0.96-1.00)

0.95 (0.93-0.96)

1996-1997

18031|24736

0.84 (0.83-0.86)

0.81 (0.80-0.82)

1995-1997

11668|13313

1.00 (0.98-1.02)

0.94 (0.92-0.96)

1998-1999

15733|27831

0.97 (0.96-0.99)

0.91 (0.90-0.93)

1997-1999

10669|14600

1.01 (0.99-1.04)

0.92 (0.90-0.94)

2000-2001

13452|31823

1.15 (1.13-1.18)

1.05 (1.03-1.07)

1999-2001

8983|15927

1.11 (1.08-1.13)

0.97 (0.95-1.00)

-

-

-

-

Birthcohort 1

   

Birthcohort 1

   

1921-1922

1599|1117

Ref.

Ref.

1924-1925

1620|1401

Ref.

Ref.

1923-1924

3276|2334

1.02 (0.93-1.13)

1.02 (0.93-1.13)

1926-1927

3359|3008

1.01 (0.93-1.11)

1.04 (0.96-1.14)

1925-1926

4508|3258

1.04 (0.94-1.15)

1.05 (0.95-1.16)

1928-1929

4972|4721

1.10 (1.01-1.20)

1.19 (1.09-1.30)

1927-1928

5285|4026

1.11 (1.00-1.22)

1.12 (1.01-1.24)

1930-1931

6579|6518

1.21 (1.11-1.32)

1.35 (1.24-1.48)

1929-1930

6047|4746

1.13 (1.03-1.25)

1.15 (1.04-1.28)

1932-1933

6323|7672

1.42 (1.30-1.54)

1.70 (1.55-1.86)

1931-1932

6166|5315

1.26 (1.14-1.39)

1.28 (1.15-1.42)

1934-1935

6415|8665

1.54 (1.42-1.68)

1.98 (1.81-2.17)

1933-1934

5880|5270

1.32 (1.20-1.46)

1.35 (1.21-1.50)

1936-1937

6573|9729

1.77 (1.63-1.92)

2.40 (2.19-2.63)

1935-1936

5705|5888

1.51 (1.36-1.66)

1.53 (1.37-1.70)

1938-1939

6529|10507

1.99 (1.83-2.17)

2.83 (2.58-3.11)

1937-1938

5547|6556

1.71 (1.55-1.89)

1.71 (1.53-1.90)

1940-1941

6588|12407

2.20 (2.03-2.39)

3.18 (2.90-3.50)

1939-1940

5716|7490

1.91 (1.73-2.10)

1.86 (1.67-2.07)

1942-1943

6638|14842

2.76 (2.55-3.00)

3.90 (3.54-4.28)

1941-1942

4300|7531

2.56 (2.32-2.82)

2.48 (2.22-2.76)

1944-1945

4686|13950

3.27 (3.01-3.55)

4.63 (4.21-5.10)

1943-1944

3270|7371

3.27 (2.97-3.61)

3.12 (2.80-3.48)

1946-1947

2429|9351

4.23 (3.88-4.61)

5.89 (5.32-6.51)

1945-1946

2032|6151

4.40 (3.98-4.87)

4.15 (3.71-4.64)

1948-1949

875|4578

5.93 (5.37-6.55)

7.68 (6.86-8.61)

1947-1948

805|3400

6.21 (5.55-6.95)

5.72 (5.05-6.47)

-

-

-

-

1949-1950

90|391

6.22 (4.88-7.92)

5.41 (4.22-6.94)

-

-

-

-

  1. Mammography screening program of Copenhagen (1991–2001) and Funen (1994–2001), Denmark.
  2. *F/MD: F=fatty mammographic density; MD=mixed/dense mammographic density.
  3. 1Adjusted for screening age.
  4. 2Adjusted for birth cohort.