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Table 1 Percent (%) MM tumor distribution a

From: Microspheres targeted with a mesothelin antibody and loaded with doxorubicin reduce tumor volume of human mesotheliomas in xenografts

  Saline APMS-MB DOX low (0.05 mg/kg) APMS-MB-DOX (0.05 mg/kg) DOX high (0.2 mg/kg)
Injection site 4.17 2.38 4.17 5.56 0.00
Pleura 0.00 0.00 3.33 0.00 0.00
Diaphragm 4.76 0.00 0.00 0.00 0.00
Esophagus 0.00 0.00 0.00 2.78 2.38
Liver 10.91 5.16 2.78 4.86 11.62
Kidney 4.44 3.97 6.11 9.33 8.49
Gut 8.33 19.60 12.36 15.56 4.17
Stomach 11.67 13.10 18.06 15.63 7.45
Spleen 4.52 14.21 11.25 20.38 7.04
Intestine 26.43 28.89 25.00 14.64 36.47
Bladder 0.00 0.00 0.00 0.00 2.78
Ovaries/Testes/Vas deferens 24.76 12.70 16.94 11.27 19.60
  1. aAs measured by the average percent (%), per treatment group, of the number tumors recovered found attached to or adjacent to respective organs and areas.