Radiation-induced temporal lobe injury after intensity modulated radiotherapy in nasopharyngeal carcinoma patients: a dose-volume-outcome analysis

Table 3 Summary of temporal lobe radiation tolerance expressed as V _10-75 using paired t-tests and ROC curve

	Area under ROC curve	β	P	Lower limit	Upper limit	Cutoff point (%)	Sensitivity	Specificity
V₁₀*	0.555	0.093	0.552	0.374	0.736
V₂₀	0.647	0.091	0.11	0.47	0.825
V₂₅	0.687	0.087	0.042	0.517	0.858	23.325	0.7	0.75
V₃₀	0.74	0.084	0.009	0.575	0.905	19.225	0.75	0.8
V₃₅	0.729	0.087	0.013	0.558	0.899	15.09	0.75	0.8
V₄₀	0.78	0.08	0.002	0.623	0.937	10.53	0.8	0.8
V₄₅	0.798	0.076	0.001	0.649	0.946	8.537	0.8	0.85
V₅₀	0.825	0.7	0.000	0.687	0.936	7.114	0.8	0.9
V₅₅	0.855	0.062	0.000	0.733	0.977	5.27	0.8	0.9
V₆₀	0.85	0.066	0.000	0.72	0.98	2.72	0.85	0.85
V₆₅	0.85	0.068	0.000	0.716	0.984	1.44	0.85	0.85
V₇₀	0.835	0.071	0.000	0.696	0.974	0.379	0.85	0.85

Abbreviation: ROC Receiver operating characteristic.
*V₁₀ is the volume of the temporal lobe that received more than 10 Gy; other volumes are indicated in a similar manner.

ISSN: 1471-2407