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Table 3 Summary of temporal lobe radiation tolerance expressed as V 10-75 using paired t-tests and ROC curve

From: Radiation-induced temporal lobe injury after intensity modulated radiotherapy in nasopharyngeal carcinoma patients: a dose-volume-outcome analysis

  Area under ROC curve β P Lower limit Upper limit Cutoff point (%) Sensitivity Specificity
V10* 0.555 0.093 0.552 0.374 0.736    
V20 0.647 0.091 0.11 0.47 0.825    
V25 0.687 0.087 0.042 0.517 0.858 23.325 0.7 0.75
V30 0.74 0.084 0.009 0.575 0.905 19.225 0.75 0.8
V35 0.729 0.087 0.013 0.558 0.899 15.09 0.75 0.8
V40 0.78 0.08 0.002 0.623 0.937 10.53 0.8 0.8
V45 0.798 0.076 0.001 0.649 0.946 8.537 0.8 0.85
V50 0.825 0.7 0.000 0.687 0.936 7.114 0.8 0.9
V55 0.855 0.062 0.000 0.733 0.977 5.27 0.8 0.9
V60 0.85 0.066 0.000 0.72 0.98 2.72 0.85 0.85
V65 0.85 0.068 0.000 0.716 0.984 1.44 0.85 0.85
V70 0.835 0.071 0.000 0.696 0.974 0.379 0.85 0.85
  1. Abbreviation: ROC Receiver operating characteristic.
  2. *V10 is the volume of the temporal lobe that received more than 10 Gy; other volumes are indicated in a similar manner.