Inclusion criteria | Exclusion criteria |
---|---|
Female | Presently using sex hormones |
50-69Ā years of age | Use of beta-blockers or oral corticosteroids |
Postmenopausal (last menses >12Ā months) | Smoking |
Body mass index (BMI) 25ā35Ā m/kg2 | Alcohol or drug abuse |
Sedentary lifestyle (<2Ā hours/week of at least moderately intensive activities (ā„4 MET)) | Diagnosed with breast cancer (present or history) |
Willing to be randomly assigned to one of the three study arms | Diagnosed with other cancer (present or <5Ā years of history), except fornon-melanoma skin cancer |
Informed consent for all screening and study activities | Diabetes mellitus or other (unstable) endocrine related diseases |
Ā | Any disorder that might impede participation in the exercise programme |
Ā | Following, or intention to follow, a structured weight loss programme elsewhere |
Ā | Investigators opinion (successful fulfilling of the programme is highly unlikely) |