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Design of the SHAPE-2 study: the effect of physical activity, in addition to weight loss, on biomarkers of postmenopausal breast cancer risk

  • Willemijn AM van Gemert1Email author,
  • Jolein I Iestra1,
  • Albertine J Schuit2, 3,
  • Anne M May1,
  • Tim Takken4, 5,
  • Wouter B Veldhuis6,
  • Job van der Palen7, 8,
  • Harriët Wittink9,
  • Petra HM Peeters1 and
  • Evelyn M Monninkhof1
BMC Cancer201313:395

Received: 2 May 2013

Accepted: 21 August 2013

Published: 23 August 2013

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Open Peer Review reports

Pre-publication versions of this article and author comments to reviewers are available by contacting

Original Submission
2 May 2013 Submitted Original manuscript
8 May 2013 Author responded Author comments - Willemijn AM Van Gemert
Resubmission - Version 2
8 May 2013 Submitted Manuscript version 2
21 Aug 2013 Editorially accepted
23 Aug 2013 Article published 10.1186/1471-2407-13-395

How does Open Peer Review work?

Open peer review is a system where authors know who the reviewers are, and the reviewers know who the authors are. If the manuscript is accepted, the named reviewer reports are published alongside the article. Pre-publication versions of the article and author comments to reviewers are available by contacting All previous versions of the manuscript and all author responses to the reviewers are also available.

You can find further information about the peer review system here.

Authors’ Affiliations

Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
Division of Public Health and Health Care, National Institute for Public Health and the Environment, Bilthoven, The Netherlands
Department of Health Sciences and EMGO Institute for Health and Care Research, VU University, Amsterdam, The Netherlands
Shared Utrecht Pediatric Exercise Research (SUPER) Lab, Utrecht University, Utrecht, The Netherlands
Child Development & Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht, Utrecht, The Netherlands
Department of Radiology, University Medical Center, Utrecht, The Netherlands
Medisch Spectrum Twente Hospital, Department of Epidemiology, Enschede, The Netherlands
Department of Research Methodology, Measurement, and Data Analysis, University of Twente, Enschede, The Netherlands
Research group Lifestyle and Health, Faculty of Health Care, Utrecht University of Applied Sciences, Utrecht, The Netherlands