|
Gene
|
Percentage of somatic alterationsBin
|
|---|
|
Breast (482C)
|
Colorectal (212C)
|
Lung (178C)
|
Ovarian (316C)
|
|---|
|
nsSNP
|
Del
|
Amp
|
nsSNP
|
Del
|
Amp
|
nsSNP
|
Del
|
Amp
|
nsSNP
|
Del
|
Amp
|
|---|
|
SMC1A
|
0.8
|
0.0
|
0.0
|
4.2
|
0.0
|
0.0
|
1.1
|
0.0
|
0.0
|
1.3
|
0.0
|
0.0
|
|
SMC3
|
0.2
|
0.2
|
0.0
|
1.4
|
0.9
|
0.0
|
2.8
|
0.6
|
0.0
|
0.3
|
0.0
|
0.0
|
|
RAD21
|
0.6
|
0.0
|
13.9
|
2.8
|
0.0
|
1.9
|
1.7
|
0.0
|
0.0
|
0.3
|
0.6
|
18.0
|
|
STAG2
|
1.2
|
0.0
|
0.0
|
2.8
|
0.0
|
0.0
|
3.4
|
0.0
|
0.0
|
0.9
|
0.0
|
0.0
|
|
PTTG1
B
|
0.0
|
0.4
|
0.2
|
0.5
|
0.0
|
0.0
|
1.1
|
0.6
|
0.0
|
0.0
|
0.0
|
0.9
|
|
ESPL1
C
|
1.5
|
0.0
|
0.2
|
3.3
|
0.0
|
0.0
|
4.5
|
0.0
|
0.6
|
0.0
|
0.3
|
0.6
|
-
AOnly the Cancer Genome Atlas (TCGA) data is shown [21–24].
-
Bnon-synonymous single nucleotide polymorphism (nsSNP), homozygous deletion (Del), gene amplification (Amp).
-
CThe total number of tumors sequenced is indicated within parentheses.
