|
CNB
|
OEB
|
Concordance rate (%)
|
Kappa
|
|---|
|
(P value)
|
|---|
|
Using Ki67 = 14% as cutoff value for determining Luminal A and B in HR+/HER2- diseases
|
|
4 Subtypes
|
Luminal A
|
Luminal B
|
TNBC
|
HER2+
|
77.2
|
0.658 (<0.001)
|
|
Luminal A
|
65
|
32
|
0
|
0
| | |
|
Luminal B
|
15
|
106
|
7
|
7
| | |
|
TNBC
|
0
|
1
|
37
|
1
| | |
|
HER2+
|
0
|
4
|
1
|
22
| | |
|
5 Subtypes
|
Luminal A
|
Luminal B
|
TNBC
|
HER2+
|
75.8
|
0.679 (<0.001)
|
|
HER2-
|
HER2+
|
|
Luminal A
|
65
|
31
|
1
|
0
|
0
| | |
|
Luminal B
|
|
HER2-
|
14
|
72
|
3
|
7
|
1
| | |
|
HER2+
|
1
|
1
|
30
|
0
|
6
| | |
|
TNBC
|
1
|
0
|
0
|
37
|
1
| | |
|
HER2+
|
0
|
0
|
4
|
1
|
22
| | |
|
Using Ki67 = 20% as cutoff value for determining Luminal A and B in HR+/HER2- diseases
|
|
4 Subtypes
|
Luminal A
|
Luminal B
|
TNBC
|
HER2+
|
79.2
|
0.692 (<0.001)
|
|
Luminal A
|
110
|
31
|
0
|
0
| | |
|
Luminal B
|
10
|
67
|
7
|
7
| | |
|
TNBC
|
1
|
0
|
37
|
1
| | |
|
HER2+
|
0
|
4
|
1
|
22
| | |
|
5 Subtypes
|
Luminal A
|
Luminal B
|
TNBC
|
HER2+
|
78.2
|
0.699 (<0.001)
|
|
HER2-
|
HER2+
|
|
Luminal A
|
110
|
29
|
2
|
0
|
0
| | |
|
Luminal B
|
|
HER2-
|
9
|
34
|
2
|
7
|
1
| | |
|
HER2+
|
1
|
1
|
30
|
0
|
6
| | |
|
TNBC
|
1
|
0
|
0
|
37
|
1
| | |
|
HER2+
|
0
|
0
|
4
|
1
|
22
| | |
-
Abbreviation: CNB, core needle biopsy; OEB, open excision biopsy; HR, hormonal receptor; TNBC, triple negative breast cancer.
