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Table 2 Tumor characteristics for CNB and OEB results

From: Preoperative core needle biopsy is accurate in determining molecular subtypes in invasive breast cancer

Characteristic No. (%) P value
CNB OEB
Pathological type    0.190
  Invasive ductal carcinoma 260 (87.2) 269 (90.3)  
  Invasive lobular carcinoma 12 (4.0) 11 (3.7)  
  Mixed carcinoma 11 (3.7) 3 (1.0)  
  Others 15 (5.0) 15 (5.0)  
Histological grading    0.009
  I 6 (2.0) 4 (1.3)  
  II 138 (46.3) 151 (50.7)  
  III 97 (32.6) 114 (38.3)  
  NA 57 (19.1) 29 (9.7)  
Estrogen Receptor    0.294
  Negative 67 (22.5) 78 (26.2)  
  Positive 231 (77.5) 220 (73.8)  
Progesterone Receptor    0.502
  Negative 120 (40.3) 112 (37.6)  
  Positive 178 (59.7) 186 (62.4)  
HER2    0.768
  Negative 233 (78.2) 230 (77.2)  
  Positive 65 (21.8) 68 (22.8)  
Ki67 (%, mean) 26.8 (1-90) 29.3 (1-90) 0.046
  <14 112 (37.6) 89 (29.9)  
  ≥14 186 (62.4) 209 (70.1)  
Hormonal receptor    0.386
  Negative 66 (22.1) 75 (25.2)  
  Positive 232 (77.9) 223 (74.8)  
Molecular subtype    0.484*
  Luminal A 97 (32.6) 80 (26.8)  
  Luminal B 135 (45.4) 143 (48.0)  
    Luminal B (HER2-) 97 (32.6) 105 (35.2)  
    Luminal-HER2+ 38 (12.8) 38 (12.8)  
  Triple negative 39 (13.1) 45 (15.1)  
  HER2 positive 27 (9.1) 30 (10.1)  
  1. Abbreviation: CNB, core needle biopsy; OEB, open excision biopsy; NA, not available;
  2. *: calculated with four subtypes classification.