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Table 2 Tumor characteristics for CNB and OEB results

From: Preoperative core needle biopsy is accurate in determining molecular subtypes in invasive breast cancer

Characteristic

No. (%)

P value

CNB

OEB

Pathological type

  

0.190

  Invasive ductal carcinoma

260 (87.2)

269 (90.3)

 

  Invasive lobular carcinoma

12 (4.0)

11 (3.7)

 

  Mixed carcinoma

11 (3.7)

3 (1.0)

 

  Others

15 (5.0)

15 (5.0)

 

Histological grading

  

0.009

  I

6 (2.0)

4 (1.3)

 

  II

138 (46.3)

151 (50.7)

 

  III

97 (32.6)

114 (38.3)

 

  NA

57 (19.1)

29 (9.7)

 

Estrogen Receptor

  

0.294

  Negative

67 (22.5)

78 (26.2)

 

  Positive

231 (77.5)

220 (73.8)

 

Progesterone Receptor

  

0.502

  Negative

120 (40.3)

112 (37.6)

 

  Positive

178 (59.7)

186 (62.4)

 

HER2

  

0.768

  Negative

233 (78.2)

230 (77.2)

 

  Positive

65 (21.8)

68 (22.8)

 

Ki67 (%, mean)

26.8 (1-90)

29.3 (1-90)

0.046

  <14

112 (37.6)

89 (29.9)

 

  ≥14

186 (62.4)

209 (70.1)

 

Hormonal receptor

  

0.386

  Negative

66 (22.1)

75 (25.2)

 

  Positive

232 (77.9)

223 (74.8)

 

Molecular subtype

  

0.484*

  Luminal A

97 (32.6)

80 (26.8)

 

  Luminal B

135 (45.4)

143 (48.0)

 

    Luminal B (HER2-)

97 (32.6)

105 (35.2)

 

    Luminal-HER2+

38 (12.8)

38 (12.8)

 

  Triple negative

39 (13.1)

45 (15.1)

 

  HER2 positive

27 (9.1)

30 (10.1)

 
  1. Abbreviation: CNB, core needle biopsy; OEB, open excision biopsy; NA, not available;
  2. *: calculated with four subtypes classification.