Table 2 Base-case costs estimates ($, year 2012 values) and utilities
Parameter | Median | Range | Description and references |
|---|---|---|---|
Cost of EGFR genotyping per patient | 507.9 | 381–634.9 | Local charge |
Cost of gefitinib per 250 mg ($) | 77.8 | 38.9–77.8* | Local charge |
Cost of follow-up per unit ($) | 55.6 | 41.7–69.4 | [34] |
Cost of 2nd-line chemotherapy per cycle ($) | 2352.7 | 1921.1–4383.3 | Calculation |
Cost of palliative care in end-of-life treatment ($) | 3664.3 | 21.4–48750.2 | Calculation |
Cost of supportive care per cycle ($) | 337.5 | 158.7–793.7 | Calculation |
Cost of SAEs in platinum-based chemotherapy per cycle ($) | 507.4 | 189.7–825.0 | Calculation |
Expenditures of SAEs in maintenance treatment per cycle | |||
Cost of SAEs in Gefitinib strategy per cycle ($) | Formula# | Calculation | |
Utilities | |||
Utility of PFS | 0.65 | 0.26–0.87 | [29] |
Utility of OS | 0.47 | 0.19–0.58 | [29] |