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Table 1 Mass transitions and method statistics for the determination of plasma SAM and SAH

From: Plasma S-adenosylmethionine, DNMTpolymorphisms, and peripheral blood LINE-1 methylation among healthy Chinese adults in Singapore

       

Inter-assay precision

Analyte

Analyte

Labeled

Labeled isotope

Retention time

LOQ

Calibration

Level 1

Level 2

 

MRM (m/z)

isotope

MRM (m/z)

(minutes)

(nmol/L)

curve

(CV%)

(CV%)

SAM

399 → 250

2H3-SAM

402 → 250

7.1

5

400 – 25 nmol/L

9.2

6.2

SAH

385 → 136

2H4-SAH

389 → 138

6.8

5

400 – 25 nmol/L

10.4

5.9

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BMC Cancer

ISSN: 1471-2407

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