Table 3 Molecular fingerprint of LGGs composed by the selected 15 genes

FOXG1 / 14q13

forkhead box G1

GO:0007417 CNS development GO:0022008 neurogenesis

GO:0030900 forebrain development GO:0048699 generation of neurons

GO:0021954 CNS neuron development GO:0021953 CNS neuron differentiation

GO:0048666 neuron development GO:0007423 sensory organ development

GO:0043583 ear development GO:0009953 dorsal/ventral pattern formation

GO:0006355 regulation of transcription, DNA-dependent

GO:0051252 regulation of RNA metabolic process

GO:0045449 regulation of transcription

GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid

GO:0048667 cell morphogenesis involved in neuron differentiation

GO:0048812 neuron projection morphogenesis

GO:0048858 cell projection morphogenesis GO:0032990 cell part morphogenesis

GO:0031175 neuron projection development

GPR17 / 2q21

G protein-coupled receptor 17

GO:0007165 signal trasduction

GO:0007186 G-protein coupled receptor protein signaling pathway

CXCL14 / 5q31

chemokine (C-X-C motif)

GO:0006995 immune response GO: 0006935 chemotaxis

ligand 14

GO:0007267 cell-cell signaling GO:0007165 signal trasduction

ARX / Xp21

aristaless related homeobox

GO:0007417 CNS development, GO:0022008 neurogenesis

GO:0030900 forebrain development, GO:0048699 generation of neurons

GO:0021954 CNS neuron development, GO:0021987 cerebral cortex development

GO:0021543 pallium development

GO:0006355 regulation of transcription, DNA-dependent

GO:0051252 regulation of RNA metabolic process

GO:0045449 regulation of transcription

GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid

GO:0048667 cell morphogenesis involved in neuron differentiation

GO:0048812 neuron projection morphogenesis

GO:0048858 cell projection morphogenesis

GO:0032990 cell part morphogenesis

GO:0031175 neuron projection development

LHX2 / 9q33q34.1

LIM homeobox 2

GO:0007417 CNS development GO:0022008 neurogenesis

GO:0030900 forebrain development GO:0048699 generation of neurons

GO:0048666 neuron development GO:0009953 dorsal/ventral pattern formation

GO:0006355 regulation of transcription, DNA-dependent

GO:0051252 regulation of RNA metabolic process

GO:0045449 regulation of transcription

GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid

GO:0048667 cell morphogenesis involved in neuron differentiation

GO:0048812 neuron projection morphogenesis

GO:0048858 cell projection morphogenesis

GO:0032990 cell part morphogenesis, GO:0031175 neuron projection development

TIMP4 / 3p25

TIMP metallopeptidase

GO:0007417 CNS development GO:0009725 response to hormone stimulus

inhibitor 4

GO:0032496 response to lipopolysaccharide

GO:0034097 response to cytokine stimulus

APOD / 3q26.2qter

apolipoprotein D

GO.0006629 lipid metabolic process

PTGD2S / 9q34.2-34.3

prostaglandin D2 synthase

GO:0006633 fatty acid biosynthetic process

21 kDa (brain)

GO:0006810 transport

SDC3 / 1pter-p22.3

syndecan 3

GO:0007155 cell adhesion

NRXN2 / 11q13

neurexin 2

GO:0007268 synaptic trasmission GO:0007269 neurotransmitter secretion

GO:0007416 synapse assembly GO:0007155 cell adhesion

SNX22 / 15q22.31

sorting nexin 22

GO:0007165 signal trasduction GO:0007154 cell comunication

ZFHX4 / 8q21.11

zinc finger homeobox 4

GO:0006355 regulation of transcription, DNA-dependent

GO:0051252 regulation of RNA metabolic process

GO:0045449 regulation of transcription

GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid

GO:0015031 protein transport

SPOCK1 / 5q31

testican 1

GO:0007417 CNS development GO:0007165 signal trasduction

GO:0007155 cell adhesion

ABBA1 / 16q22.1

metastasis suppressor 1 like

GO:0007165 signal trasduction

FOSB / 19q13.32

FBJ murine osteosarcoma

GO:0006355 regulation of transcription, DNA-dependent

viral oncogene homolog B

GO:0051252 regulation of RNA metabolic process

GO:0045449 regulation of transcription

GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid