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Figure 4 | BMC Cancer

Figure 4

From: Effectivity of pazopanib treatment in orthotopic models of human testicular germ cell tumors

Figure 4

Pazopanib inhibits tumor growth in a xenograft orthotopic model of choriocarcinoma testicular germ cell tumor and synergizes with lapatinib. Mice orthotopically implanted with the TGT38 choriocarinoma were treated daily with vehicle, 100 mg/kg pazopanib, 100 mg/kg lapatinib or a combination of both for 14 days. Final tumor volumes are illustrated by a boxplot. **, p < 0.01; ***, p < 0.001 (two-tail Mann–Whitney U test). All treatments showed significant inhibition with respect to the control group.

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