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Table 1 Tumor characterization

From: Loss of Akt1 or Akt2 delays mammary tumor onset and suppresses tumor growth rate in MTB-IGFIR transgenic mice

Genotype # of mice Tumor onset (days) Specific growth rate # of tumors at time of death # of mice with lung metastases
MTB-IGFIR 11 35.5 ± 2.0 0.14 ± 0.02 3.2 ± 0.2 2/11
MTB-IGFIR/Akt1−/− 6 47.3 ± 3.1* 0.07 ± 0.01* 2.8 ± 0.8 1/6
MTB-IGFIR/Akt2−/− 6 43.6 ± 3.6* 0.09 ± 0.02* 3.5 ± 0.6 1/6
  1. *significantly different from WT as determined by a Duncan’s test using WT, Akt1−/− and Akt2−/− mice.