Figure 6From: Loss of Akt1 or Akt2 delays mammary tumor onset and suppresses tumor growth rate in MTB-IGFIR transgenic mice Cytokeratin expression in mammary tumors from MTB-IGFIR, MTB-IGFIR/Akt1 -/- and MTB-IGFIR/Akt2 -/- mice. Immunohistochemistry for cytokeratin 8 (A-C), cytokeratin 5 (D-F) or cytokeratin 14 (G-I) in mammary tumors from MTB-IGFIR mice (A,D,G), MTB-IGFIR/Akt1−/− mice (B,E,H) or MTB-IGFIR/Akt2−/− mice (C,F,I). The brown color indicates the presence of each protein while the nuclei of the cells are blue due to hematoxylin staining. Scale bars, 100 μm.Back to article page