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Table 2 Median IC 50 for different diagnoses in response to VLX40

From: Screening for phenotype selective activity in multidrug resistant cells identifies a novel tubulin active agent insensitive to common forms of cancer drug resistance

Diagnosis

Median IC50(μM)

Number of samples

Breast cancer

>34

8

Colon cancer

>34

5

Lung cancer

>34

6

Renal cancer

>34

8

Ovarian cancer

>34

19

AML

1.56

8

ALL

3.21

19

CML

0.98

2

CLL

2.18

11

NHL

0.51

13

PBMC

16.3

4