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Table 2 Univariate and multivariate logistic regression estimating odds ratio (OR) of developing pneumonia acquired during radiotherapy (PNRT) among variables

From: Incidence of pneumonia and risk factors among patients with head and neck cancer undergoing radiotherapy

Variable

Univariate OR

(95% CI)

Multivariate OR

(95% CI)

Male (vs. Female)

1.64

(1.30~2.07)

1.77

(1.40~2.24)

Age (vs. < 50 years)

    

  50~64

1.73

(1.45~2.06)

1.67

(1.40~2.00)

  ≥ 65

3.66

(3.04~4.40)

3.54

(2.93~4.28)

Hospital level (vs. District hospital/clinic)

  

  Medical center

1.64

(1.25~2.16)

1.69

(1.29~2.23)

  Regional hospital

1.68

(1.25~2.25)

1.68

(1.25~2.26)

Treatment (vs. no)

    

  Neck dissection

0.75

(0.61~0.91)

0.77

(0.63~0.94)

  Gastrostomy

3.09

(2.06~4.63)

2.94

(1.94~4.44)

Comorbidity (vs. no)

    

  Stroke

2.23

(1.63~3.05)

1.35

(0.98~1.87)

  Parkinson’s disease

5.18

(1.93~13.9)

3.01

(1.09~8.30)

  GERD

1.54

(1.15~2.07)

1.48

(1.09~1.99)

Cancer site

    

  Lip

0.63

(0.23–1.71)

0.63

(0.23–1.73)

  Tongue

1.13

(0.91–1.40)

1.28

(1.02–1.61)

  Salivary gland

0.74

(0.30–1.81)

0.57

(0.23–1.40)

  Gum

0.85

(0.53–1.36)

0.70

(0.43–1.14)

  Mouth floor

1.67

(0.94–2.95)

1.75

(0.98–3.13)

  Buccal mucosa

1.31

(1.11–1.55)

1.28

(1.07–1.53)

  Oropharynx

1.90

(1.54–2.36)

1.67

(1.36–2.10)

  Nasopharynx

0.46

(0.39–0.53)

0.46

(0.39–0.54)

  Hypopharynx

2.33

(1.86–2.93)

1.74

(1.37–2.21)

  Unknown

1.21

(0.65–2.23)

1.10

(0.59–2.04)

  1. GERD gastroesophageal reflux disease.