First description of seasonality of birth and diagnosis amongst teenagers and young adults with cancer aged 15–24 years in England, 1996–2005

Table 3 Sex-adjusted monthly seasonality of birth in cancer amongst 15–24 year olds in England, 1996-2005

		Harmonic Model Results²
Diagnostic group¹	Cases ( N)	Max	Min	P-value³	GOF ( P-value)	Period (Months)
Leukaemia	1299	Apr, Oct	Jan, Jul	0.242	0.917	6
ALL	591	Apr, Oct	Jan, Jul	0.242	0.917	6
AML	463	Jan, Jul	Apr, Oct	0.560	0.356	6
CML	147	Jan, Jul	Apr, Oct	0.775	0.650	12
Other Leukaemia	98	Jan	Jul	0.279	0.527	12
Lymphoma	3070	Jan, Jul	Apr, Oct	0.428	0.281	6
Hodgkin Lymphoma	2079	Mar	Sep	0.460	0.100	12
Non-Hodgkin Lymphoma	991	Jan, Jul	Apr, Oct	0.080	0.468	6
CNS Tumours	1882	May, Nov	Feb, Aug	0.155	0.368	6
Astrocytoma	629	Jan	Jul	0.119	0.988	12
Other Gliomas	195	May, Nov	Feb, Aug	0.015	0.874	6
Ependymoma	99	Dec, Jun	Mar, Sep	0.158	0.092	6
Medulloblastoma	111	Jan, Jul	Apr, Oct	0.257	0.446	6
Other CNS	702	Apr	Oct	0.706	0.116	12
Unspecified CNS	146	Dec	Jun	0.753	0.616	12
Leukaemia, Lymphoma, CNS tumours	6251	Jan	Jul	0.339	0.405	12

¹Based on the classification scheme for tumours diagnosed in adolescents and young adults [12].
²Best fitting model is presented in each case, basedon comparison of Akaike’s Information Criterion between models with differing periods.
³Statistical significance of the peaks.
GOF: Goodness of fit statistic.

ISSN: 1471-2407