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Table 2 Sex-adjusted monthly seasonality of diagnosis in cancer amongst 15–24 year olds in England, 1996–2005

From: First description of seasonality of birth and diagnosis amongst teenagers and young adults with cancer aged 15–24 years in England, 1996–2005

 

Harmonic model results2

Diagnostic group1

Cases ( N)

Max

Min

P-value3

GOF ( P-value)

Period (Months)

Leukaemia

1299

Oct

Apr

0.266

0.461

12

 ALL

591

Oct

Apr

0.253

0.780

12

 AML

463

Nov

May

0.498

0.354

12

 CML

147

Jan, Jul

Apr, Oct

0.651

0.690

6

 Other Leukaemia

98

Feb, Aug

May, Nov

0.424

0.528

6

Lymphoma

3070

Feb

Aug

0.008

0.716

12

 Hodgkin Lymphoma

2079

Feb

Aug

<0.001

0.580

12

 Non-Hodgkin Lymphoma

991

Feb

Aug

0.667

0.968

12

CNS Tumours

1882

Sep

Mar

0.653

0.638

12

 Astrocytoma

629

Dec, Jun

Mar, Sep

0.479

0.730

6

 Other Gliomas

195

Sep

Mar

0.091

0.942

12

 Ependymoma

99

Jan

Jul

0.612

0.988

12

 Medulloblastoma

111

Dec, Jun

Mar, Sep

0.080

0.640

6

 Other CNS

702

Dec, Jun

Mar, Sep

0.010

0.305

6

 Unspecified CNS

146

May, Nov

Feb, Aug

0.448

0.657

6

Leukaemia, Lymphoma, CNS tumours

6251

Jan

Jul

0.241

0.793

12

  1. 1 Based on the classification scheme for tumours diagnosed in adolescents and young adults [12].
  2. 2Best fitting model is presented in each case, based on comparison of Akaike’s Information Criterion between models with differing periods.
  3. 3Statistical significance of the peaks.
  4. GOF: Goodness of fit statistic.