Figure 3

Clustering’s on differentially expressed miRNAs between TZ and PZ tissues. Clustering’s are based on miRNAs found to be differentially expressed (before multiple testing adjustment) between TZ and PZ samples from normal tissue ( A ) and malignant tissue ( B ). The clustering of normal samples resulted in three major clusters, one with seven TZ samples, one with eight PZ samples, and one mixed cluster containing three TZ and two PZ samples (marked with red box). The clustering of malignant samples resulted in two major clusters, of which one was mixed (i.e. contained three misplaced TZ samples, red boxes) and one was a small homogeneous TZ cluster. Green colors are high expression values while red colors are low expression values.