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Table 3 Association between the CEACAM1 mRNA expression patterns and clinical parameters

From: Clinical and experimental studies regarding the expression and diagnostic value of carcinoembryonic antigen-related cell adhesion molecule 1 in non-small-cell lung cancer

Groups

No.

Tumour tissue

Normal tissue

  

Median (P50)

Range

P value

Median (P50)

Range

P value

Age

       

≥60

13

0.0293

5.60 × 10 -4~ 0.0716

0.082

5.31 × 10 -3

2.28 × 10 -3~ 0.0172

0.828

<60

8

2.62 × 10 -3

9.25 × 10 -4~ 0.0287

6.99 × 10 -3

3.80 × 10 -4~ 0.0113

Sex

       

Male

12

3.09 × 10 -3

5.60 × 10 -4~ 0.0373

0.028*

4.31 × 10 -3

3.80 × 10 -4~ 0.0172

0.088

Female

9

0.0293

1.36 × 10 -3~ 0.0716

8.67 × 10 -3

3.81 × 10 -3~ 0.0114

Staging***

       

Stage Ia ~ IIb

14

0.0126

5.60 × 10 -4~ 0.0693

0.332

5.61 × 10 -3

5.60 × 10 -4~ 0.0693

0.709

Stage IIIa ~ IV

7

2.09 × 10 -3

9.24 × 10 -4~ 0.716

7.87 × 10 -3

2.85 × 10 -3~ 0.0113

Grading

       

G1 ~ 2

10

0.0126

1.04 × 10 -3~ 0.716

0.439

8.60 × 10 -3

3.20 × 10 -3~ 0.172

0.020*

G3 ~ 4

11

3.21 × 10 -3

5.60 × 10 -4~ 0.422

3.81 × 10 -3

3.80 × 10 -4~ 0.0113

Histology

       

Squamous 1

5

0.00144

9.246 × 10 -4~ 0.0032

 

0.0032

3.80 × 10 -4~ 0.0171

 

Adenocarcinoma

11

0.0286

0.0013 ~ 0.072

0.003*

0.00787

0.0034 ~ 0.0114

0.585

Others**

5

0.0021

5.60 × 10 -4~ 0.014

 

0.00853

0.0023 ~ 0.011

 

Lymph node metastasis

     

node negative

7

0.0140

1.04 × 10 -3~ 0.0658

0.502

8.53 × 10 -3

3.81 × 10 -3~ 0.017

0.117

node positive

14

3.19 × 10 -3

5.60 × 10 -4~ 0.0716

4.98 × 10 -3

3.80 × 10 -4~ 0.011

Invasion depth

     

pT1 ~ pT2

17

0.0129

5.60 × 10 -4~ 0.0716

0.039*

2.12 × 10 -3

3.80 × 10 -4~ 0.0172

0.720

pT3 ~ pT4

4

1.63 × 10 -3

9.25 × 10 -4~ 3.21 × 10 -3

6.28 × 10 -3

2.85 × 10 -3~ 0.0113

  1. “1” represents squamous cell carcinoma; *P < 0.05.
  2. “**” Others represents 2 poorly differentiated carcinomas, 1 mixed histology, 1 neuroendocrine carcinoma and 1 lymphoepithelioma-like carcinoma.
  3. “***” 7th edition of the TNM classification of lung cancer by the International Association for the Study of Lung Cancer (IASLC).