Groups | No. | Tumour tissue | Normal tissue | ||||
---|---|---|---|---|---|---|---|
Median (P50) | Range | P value | Median (P50) | Range | P value | ||
Age | |||||||
≥60 | 13 | 0.0293 | 5.60 × 10 -4 ~ 0.0716 | 0.082 | 5.31 × 10 -3 | 2.28 × 10 -3 ~ 0.0172 | 0.828 |
<60 | 8 | 2.62 × 10 -3 | 9.25 × 10 -4 ~ 0.0287 | 6.99 × 10 -3 | 3.80 × 10 -4 ~ 0.0113 | ||
Sex | |||||||
Male | 12 | 3.09 × 10 -3 | 5.60 × 10 -4 ~ 0.0373 | 0.028* | 4.31 × 10 -3 | 3.80 × 10 -4 ~ 0.0172 | 0.088 |
Female | 9 | 0.0293 | 1.36 × 10 -3 ~ 0.0716 | 8.67 × 10 -3 | 3.81 × 10 -3 ~ 0.0114 | ||
Staging*** | |||||||
Stage Ia ~ IIb | 14 | 0.0126 | 5.60 × 10 -4 ~ 0.0693 | 0.332 | 5.61 × 10 -3 | 5.60 × 10 -4 ~ 0.0693 | 0.709 |
Stage IIIa ~ IV | 7 | 2.09 × 10 -3 | 9.24 × 10 -4 ~ 0.716 | 7.87 × 10 -3 | 2.85 × 10 -3 ~ 0.0113 | ||
Grading | |||||||
G1 ~ 2 | 10 | 0.0126 | 1.04 × 10 -3 ~ 0.716 | 0.439 | 8.60 × 10 -3 | 3.20 × 10 -3 ~ 0.172 | 0.020* |
G3 ~ 4 | 11 | 3.21 × 10 -3 | 5.60 × 10 -4 ~ 0.422 | 3.81 × 10 -3 | 3.80 × 10 -4 ~ 0.0113 | ||
Histology | |||||||
Squamous 1 | 5 | 0.00144 | 9.246 × 10 -4 ~ 0.0032 | 0.0032 | 3.80 × 10 -4 ~ 0.0171 | ||
Adenocarcinoma | 11 | 0.0286 | 0.0013 ~ 0.072 | 0.003* | 0.00787 | 0.0034 ~ 0.0114 | 0.585 |
Others** | 5 | 0.0021 | 5.60 × 10 -4 ~ 0.014 | 0.00853 | 0.0023 ~ 0.011 | ||
Lymph node metastasis | |||||||
node negative | 7 | 0.0140 | 1.04 × 10 -3 ~ 0.0658 | 0.502 | 8.53 × 10 -3 | 3.81 × 10 -3 ~ 0.017 | 0.117 |
node positive | 14 | 3.19 × 10 -3 | 5.60 × 10 -4 ~ 0.0716 | 4.98 × 10 -3 | 3.80 × 10 -4 ~ 0.011 | ||
Invasion depth | |||||||
pT1 ~ pT2 | 17 | 0.0129 | 5.60 × 10 -4 ~ 0.0716 | 0.039* | 2.12 × 10 -3 | 3.80 × 10 -4 ~ 0.0172 | 0.720 |
pT3 ~ pT4 | 4 | 1.63 × 10 -3 | 9.25 × 10 -4 ~ 3.21 × 10 -3 | 6.28 × 10 -3 | 2.85 × 10 -3 ~ 0.0113 |