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Table 2 Genotype and allele frequencies of the BIRC5 rs9904341 polymorphisms among the PCa cases and controls

From: Functional promoter -31G/C variant of Survivin gene predict prostate cancer susceptibility among Chinese: a case control study

Polymorphisms

Cases (n = 665)

Controls (n = 710)

P*

Adjusted OR (95%CI) †

n

%

n

%

BIRC5 (rs9904341)

      

 GG

150

22.5

205

28.9

0.014

1.00 (reference)

 CG

319

48.0

331

46.6

0.038

1.32 (1.01-1.72)

 CC

196

29.5

174

24.5

0.004

1.57 (1.17-2.13)

 CG + CC

515

77.5

505

71.1

0.008

1.40 (1.09-1.80)

 G

619

46.5

741

52.2

0.003

1.0 (reference)

 C

711

53.5

679

47.8

 

1.12 (1.04-1.20)

 P trend

    

0.004

 
  1. * Two-sided χ2 test for the either genotype distributions or allele frequencies between the cases and controls.
  2. † Adjusted for age, smoking status, drinking status, and family history of cancer in logistic regression model; 95% CI: 95% confidence interval; OR: odds ratio.
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BMC Cancer

ISSN: 1471-2407

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