Functional promoter -31G/C variant of Survivin gene predict prostate cancer susceptibility among Chinese: a case control study

Table 1 Demographic and clinical variables of prostate cancer cases and controls

Variables	Cases (n = 665)		Controls (n = 710)		P ^*
Variables	n	%	n	%	P ^*
Age (years) (Mean ± SD)	71.4 ± 8.0		71.3 ± 7.4		0.833
≤ 71	310	46.6	355	50.0	0.210
> 71	355	53.4	355	50.0
Smoking status					0.005
Never	280	42.1	353	49.7
Ever	385	57.9	357	50.3
Pack-years of smoking					<0.001
0	281	42.3	353	49.7
0-20	127	19.1	177	24.9
>20	257	38.6	180	25.4
Drinking status					0.028
Never	468	70.4	537	75.6
Ever	197	29.6	173	24.4
Family history of cancer					<0.001
No	536	80.6	655	92.2
Yes	129	19.4	55	7.8
Clinical stage
Localized	390	58.7
Advanced	275	41.3
Gleason score
<7	225	33.8
=7	221	33.2
>7	219	33.0
PSA (ng/ml)
≤20	272	40.9
>20	393	59.1

^* T-test for age distributions between the cases and controls; two-sided χ² test for others selected variables between the cases and controls.

ISSN: 1471-2407