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Figure 1 | BMC Cancer

Figure 1

From: Design and application of a novel PNA probe for the detection at single cell level of JAK2V617Fmutation in Myeloproliferative Neoplasms

Figure 1

Detection of JAK2 mutation by PNA. Detection of JAK2 V617F mutation by PNA (green signal) in CD34+ cells enriched from patients affected by Essential Thrombocytemia (ET), (A, B), Primary myelofibrosis (PMF) (C, D) Polycytemia Vera (PV) (E, F). Negative control (G, H) is represented by a non JAK2 mutated MPN patient. No specific PNA green signal can be detected in the absence of JAK2 V617F mutation.

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