Figure 1From: Design and application of a novel PNA probe for the detection at single cell level of JAK2V617Fmutation in Myeloproliferative Neoplasms Detection of JAK2 mutation by PNA. Detection of JAK2 V617F mutation by PNA (green signal) in CD34+ cells enriched from patients affected by Essential Thrombocytemia (ET), (A, B), Primary myelofibrosis (PMF) (C, D) Polycytemia Vera (PV) (E, F). Negative control (G, H) is represented by a non JAK2 mutated MPN patient. No specific PNA green signal can be detected in the absence of JAK2 V617F mutation.Back to article page