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Table 4 Joint associations of the FTO rs 9939609 and history of diabetes with respect to pancreatic cancer risk

From: Association between variations in the fat mass and obesity-associated gene and pancreatic cancer risk: a case–control study in Japan

Genotype

History of diabetes

Cases/control subjects

Age- and sex-adjusted OR

Multivariable-adjusted OR

TT

No

163/243

1.00

1.00

TA/AA

No

106/119

1.38 (0.99-1.93)

1.41 (1.00-1.98)

TT

Yes

34/26

1.76 (1.01-3.07)

1.70 (0.96-3.00)

TA/AA

Yes

24/8

4.03 (1.75-9.24)

3.70 (1.59-8.63)

    

P for interaction=0.28

  1. Cases were excluded if the onset of diabetes was within 2 years prior to the diagnosis of pancreatic cancer.
  2. Multivariable OR: adjusted for age, sex, body mass index, and cigarette smoking.