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Table 4 Comparison of visceral fat area and the liver-to-spleen density ratio between cryptogenic hepatocellular carcinoma (HCC) patients and patients with HCC of other etiologies

From: Clinical features and outcome of cryptogenic hepatocellular carcinoma compared to those of viral and alcoholic hepatocellular carcinoma

 

§Cryptogenic HCC (n = 18)

HBV-HCC (n = 36)

*p

HCV-HCC (n = 36)

**p

¶ ALC-HCC

***p

      

(n = 23)

 

Age (yr) †

70.3 ± 10.6

67.4 ± 9.1

0.201

69.0 ± 8.8

0.646

67.7 ± 9.6

0.510

Gender, male††

9 (50.0)

9 (50.0)

1.000

9 (50.0)

1.000

18 (78.3)

0.097

BMI (kg/m2) †

24.7 ± 3.0

23.3 ± 3.1

0.196

22.8 ± 3.2

0.050

24.5 ± 4.9

0.415

VFA (cm2) †

134.4 ± 53.9

100.0 ± 51.3

0.037

105.0 ± 51.1

0.034

136.9 ± 64.9

0.599

Liver attenuation (HU) †

54.3 ± 5.5

53.7 ± 5.8

0.533

53.5 ± 6.7

0.441

50.7 ± 8.3

0172

Spleen attenuation (HU) †

44.0 ± 4.5

43.7 ± 4.0

0.263

45.0 ± 3.8

0.734

44.0 ± 5.0

0.743

Liver/Spleen ratio†

1.24 ± 0.14

1.23 ± 0.14

0.854

1.20 ± 0.14

0.419

1.15 ± 0.14

0.066

  1. †Expressed as the mean ± standard deviation. ††Expressed as the number of subjects (%). Values in bold, statistically significant (p < 0.05).
  2. § Available data in 18 patients. Eighteen patients with cryptogenic HCC were matched for age and sex (1:2 ratio) with HBV-HCC or HCV-HCC patients.
  3. ¶ Of 55 ALC-HCC, VFA was measured in 23 patients. ALC-HCC patients did not match with regard to age and sex with cryptogenic-HCC patients because they were mostly of male gender and because the sample sizes of each subgroup were small.
  4. HU, Hounsfield unit; VFA, Visceral fat accumulation; BMI, Body mass index.
  5. *p: Cryptogenic HCC vs. HBV-HCC.
  6. **p: Cryptogenic HCC vs. HCV-HCC.
  7. ***p: Cryptogenic HCC vs. ALC-HCC.