Figure 3
The effect of different usage modes of T 3 on sensitivity of MCF-7 to 5-Fu. (A) Only sensitivity of MCF-7 to 5-Fu in the 1st to 3rd groups pretreated with 4 ng/ml T3 significantly increased, compared with that in group treated with 5-Fu only (7th group), * P<0.05; No significant difference of inhibition ratio was found between each of the 4th to 6th groups and 7th group, * P>0.05. (B) Pretreament MCF-7 with 2 ng/ml T3 did not show significant difference of inhibition ratio between each of 1st to 6th groups and 7th group, * P>0.05. (C) The inhibition ratio of different usage modes of T3, which ranged from 8 ng/ml to 32 ng/ml. The sensitivity of MCF-7 to 5-Fu in the 1st to 3rd groups pretreated with T3 all significantly increased, * P<0.05; The MCF-7 in 4th to 6th groups successively showed significantly increased chemosensitivity, compared with that of 7th group, * P<0.05, as the T3 dose elevating from 8 ng/ml to 32 ng/ml.