The dyslipidemia-associated SNP on the APOA1/C3/A5 gene cluster predicts post-surgery poor outcome in Taiwanese breast cancer patients: a 10-year follow-up study

Table 5 APOA1 rs670 A allele carrying patients had increased odds of post-surgery disease progression

	rs670	Unadjusted		Lymph node-adjusted^a		ER/PR-adjusted^b
		OR (95% CI)	P value	OR (95% CI)	Pvalue	OR (95% CI)	P value
Recurrence	G/G	1.00	-	1.00	-	1.00	-
	G/A	2.07 (1.03-4.14)	0.041	1.57 (0.74-3.33)	0.238	2.49 (1.14-5.44)	0.022
	A/A	3.44 (1.33-8.86)	0.011	2.83 (1.05-7.61)	0.040	3.08 (1.08-8.78)	0.035
Mortality	G/G	1.00	-	1.00	-	1.00	-
	G/A	1.82 (0.74-4.48)	0.191	2.25 (0.83-6.11)	0.112	1.05 (0.4-2.76)	0.925
	A/A	6.03 (2.08-17.51)	0.001	5.14 (1.56-16.97)	0.007	4.45 (1.4-14.15)	0.010

NOTE: Data shown represent number of patients (% of n) or mean±s.d.. Bold type indicates p<0.050.
^a, adjusted for lymph node status, n=211.
^b, adjusted for ER/PR status, n=196.
Abbreviations: CI confidence interval, ER estrogen receptor, PR progesterone receptor, OR odds ratio.

ISSN: 1471-2407