Skip to main content

Table 3 APOA1 rs670 A allele carrying patients had increased odds of lymph node involvement and hormone receptor expression negativity at baseline

From: The dyslipidemia-associated SNP on the APOA1/C3/A5 gene cluster predicts post-surgery poor outcome in Taiwanese breast cancer patients: a 10-year follow-up study

  Multinominal logistic regression (using APOA1 rs670 G/G as reference)
  APOA1 rs670 G/A APOA1 rs670 A/A
  OR 95% Cl P value OR 95% Cl P value
Tumor type (using infiltrating ductal carcinoma as reference)
Ductal carcinoma in situ 0.38 0.12-1.15 0.086 0.64 0.13-3.11 0.575
Others 0.6 0.16-2.32 0.461 1.27 0.23-6.99 0.784
Unknown 0 0-0 N/A 0 0-0 N/A
Side (using right as reference)
Left 0.66 0.37-1.18 0.160 0.69 0.28-1.66 0.402
Bilateral 0.67 0.16-2.87 0.593 0.67 0.07-6.59 0.734
Tumor size (using <5cm as reference)
≥5cm 2.25 0.83-6.08 0.111 2.25 0.57-8.79 0.245
Unknown 0.59 0.28-1.26 0.173 0.67 0.21-2.21 0.515
Lymph node involvement (using positive as reference)
Negative 3.32 1.77-6.20 <0.001 2.58 1.05-6.32 0.039
Unknown 0.95 0.28-3.18 0.930 0 0-0 N/A
TMN staging (using stages 0–2 as reference)
Stages >2 2.41 0.95-6.11 0.064 1.8 0.48-6.79 0.385
Unknown 0.71 0.34-1.49 0.364 0.47 0.13-1.76 0.263
ER/PR status (using positive as reference)
Negative 1.85 0.88-3.92 0.106 4.85 1.83-12.83 0.001
Unknown 0.79 0.34-1.85 0.592 0.35 0.04-2.87 0.326
Family history (using negative as reference)
Positive 0.63 0.14-2.88 0.548 0 0-0 N/A
Unknown 1 0.30-3.40 0.997 1.3 0.24-7.09 0.765
  1. NOTE: Bold type indicates p<0.050.
  2. Abbreviations: CI confidence interval, ER estrogen receptor, PR progesterone receptor, OR odds ratio.