Figure 1
From: Overexpression of peptide deformylase in breast, colon, and lung cancers
PDF and MAP1D mRNA expression varies across human cell lines. The expression of PDF and MAP1D mRNA in normal breast (Hs578Bst), colon (CCD-18Co), lung (Hs888Lu), and prostate (PrEC) cell lines was compared to the expression in breast cancer (Hs578T), colon cancer (HT29), lung cancer (A549), and prostate cancer (PC3) cell lines, respectively. The mRNA copy numbers for PDF and MAP1D were related to cDNA standards for these two genes and then normalized to β-actin levels. PDF was significantly (denoted by “a”) elevated in the colon, lung, and prostate cancer cell lines compared to their respective normal cell lines while MAP1D was significantly (denoted by “b”) elevated only in the prostate cancer cell line. The data represent the average mRNA copy number for 3 replicate experiments ± SD.