Skip to main content

Table 1 Cervical lymph node metastasis in orthotopic HNSCC mouse model

From: Anti-lymphangiogenic properties of mTOR inhibitors in head and neck squamous cell carcinoma experimental models

 

Control

Rapamycin

Number of positive cervical lymph nodes

42/66 (63.6%)

31/68 (45.6%) *

Extent of tumor cell spread within positive lymph nodes:

  

  Extensive spread

33/42 (78.6%)

 8/31 (25.8%) ****

  Subcapsular

 9/42 (21.4%)

23/31 (74.2%) ****

  1. * - p < 0.05 (Fisher’s test).
  2. **** - p < 0.0001 (Fisher’s test).