Skip to main content
Figure 2 | BMC Cancer

Figure 2

From: Induction of chromosome instability and stomach cancer by altering the expression pattern of mitotic checkpoint genes in mice exposed to areca-nut

Figure 2

Dissected mouse and histopathology of both normal and tumor tissue of stomach following treatment with RAN with and without lime. A. Dissected mouse with (a) normal stomach and (b) tumorous stomach indicated with an arrow. Histopathology of normal (c) and tumour stomach (d,e and f) that induced by RAN extract with lime. The arrows indicate ulcerated neoplasm in (d) and tumor giant cells in (e and f). The magnification is indicated either 10X or 40X. B. Histopathology of normal and tumorous stomach of mice following RAN and RAN + lime treatment for 300 days. In all panels, “Normal” indicates mice with no tumor, “Dysplasia” indicates mice with precancerous stomach tissue. “Carcinoma” indicates mice with tumorous stomach. Dysplasia shows anisokaryosis (variation in size of nuclei) and anisocytosis (variation in size of cells). The magnification is indicated either 10X, 40X and 100X.

Back to article page