Table 5 Average methylation at imprinted genes in five samples with paired normal adjacent tissue
From: DNA methylation analysis reveals distinct methylation signatures in pediatric germ cell tumors
| Â | Ovarian Germinoma | Ovarian Teratoma | Ovarian YST | Ovarian Germinoma | Testicular YST |
|---|---|---|---|---|---|
| Â | Age 7 | Age 21 | Age 19 | Age 11 | Age 1 |
| Â | Average Methylation1 | Average Methylation1 | Average Methylation1 | Average Methylation1 | Average Methylation1 |
H19 CTCF3 | Â | Â | Â | Â | Â |
Normal | 48% | 48% | 61% | 49% | 50% |
Tumor | 13% | 8% | 63% | 14% | 26% |
H19 CTCF6 | Â | Â | Â | Â | Â |
Normal | 36% | 36% | 44% | 34% | 36% |
Tumor | 10% | 6% | 39% | 10% | 26% |
IGF2 | Â | Â | Â | Â | Â |
Normal | 54% | 53% | 68% | 31% | 63% |
Tumor | 12% | 33% | 26% | 9% | 55% |
KvDMR | Â | Â | Â | Â | Â |
Normal | 56% | 54% | 78% | 53% | 63% |
Tumor | 11% | 97% | 24% | 10% | 11% |
SNRPN | Â | Â | Â | Â | Â |
Normal | 41% | 37% | 55% | NA2 | 21% |
Tumor | 10% | 81% | 19% | 40% | 2% |
PEG3 | Â | Â | Â | Â | Â |
Normal | 34% | 39% | 54% | NA2 | 37% |
Tumor | 9% | 86% | 88% | 40% | NA2 |