Table 3 Relationship between Cx43 expression and clinicopathological factors in patients with HBV-HCC and low AFP levels
Cx43 | χ2 | PValue | |||
|---|---|---|---|---|---|
- (%) | + (%) | ||||
Gender | Male | 68(42.3%) | 71(44.6%) | 1.809 | 0.179 |
Female | 13(8.2%) | 7(4.4%) | |||
Age | > 60y | 18(11.3%) | 27(17.0%) | 3.008 | 0.083 |
≤ 60y | 63(39.6%) | 51(32.1%) | |||
Edmondson-Steiner classification | I–II | 51(32.1%) | 66(41.5%) | 9.969 | 0.002* |
III–IV | 30(18.9%) | 12(7.5%) | |||
Foci | Single | 64(40.3%) | 72(45.3%) | 5.68 | 0.017* |
Multiple | 17(10.7%) | 6(3.7%) | |||
Tumor size | > 5cm | 41(25.8%) | 48(30.1%) | 1.923 | 0.166 |
≤ 5cm | 40(25.2%) | 30(18.9%) | |||
Liver capsule invasion | No | 24(15.1%) | 32(20.1%) | 2.262 | 0.133 |
Yes | 57(35.8%) | 46(28.9%) | |||
Satellite foci | No | 73(45.9%) | 73(45.9%) | 0.636 | 0.425 |
Yes | 8(5.0%) | 5(3.2%) | |||
Cirrhosis | No | 4(2.5%) | 10(6.3%) | 3.075 | 0.080 |
Yes | 77(48.4%) | 68(42.8%) | |||
Vascular tumor thrombosis | No | 75(47.1%) | 78(49.1%) | 8.243 | 0.029* |
Yes | 6(3.8%) | 0(0%) | |||
Microvascular invasion | No | 21(27.3%) | 30(40%) | 5.422 | 0.020 |
Yes | 18(23.4%) | 8(10.3%) | |||
Child-Pugh class | A | 78(49.1%) | 78(49.1%) | 4.102 | 0.246 |
B | 3(1.8%) | 0(0%) | |||
TNM Stage | I–II | 79(49.7%) | 78(49.1%) | 1.857 | 0.405 |
III–IV | 22(13.8%) | 12(7.6%) | |||
1-year recurrence | No | 50(31.4%) | 66(41.5%) | 7.544 | 0.006* |
Yes | 31(19.5%) | 12(7.6%) | |||