Table 2 Correlation of NDRG2 expression with clinical histopathological characteristics in 143 ESCC specimens

Gender

   Male

57 (60.0)

38 (40.0)

0.154^a

   Female

26 (54.2)

22 (45.8)

Age(years)

   ≤60

50 (64.1)

28 (35.9)

0.127 ^a

   >60

33 (50.8)

32 (49.2)

Cigarette smoking

   No

33 (64.7)

18 (35.3)

0.289 ^a

   Yes

50 (54.3)

42 (45.7)

Alcohol drinking

   No

17 (45.9)

20 (54.1)

0.121 ^a

   Yes

66 (62.3)

40 (37.7)

Clinical stage

   I

1 (20.0)

4 (80.0)

0.009^b

   IIA

29 (45.3)

35 (54.7)

   IIB

15 (65.2)

8 (34.8)

   III

28 (73.7)

10 (26.3)

   IV

10 (76.9)

3 (23.1)

T classification

   T1

1 (11.1)

8 (88.9)

<0.0001^b

   T2

23 (44.2)

29 (55.8)

   T3

43 (68.3)

20 (31.7)

   T4

16 (84.2)

3 (15.8)

N classification

   N0

22 (36.1)

39 (63.9)

<0.0001^b

   N1

50 (72.5)

19 (27.5)

   N2

11 (84.6)

2 (15.4)

M classification

   M0

72 (55.4)

58 (44.6)

0.036^a

   M1

11 (84.6)

2 (15.4)

Histological differentiation

   Well

18 (40.0)

27 (60.0)

0.005^b

   Moderate

30 (60.0)

20 (40.0)

   Poor

35 (72.9)

13 (27.1)