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Table 2 Most frequent unrelated and related adverse events after treatment with irradiation plus nimotuzumab or placebo

From: Radiotherapy plus nimotuzumab or placebo in the treatment of high grade glioma patients: results from a randomized, double blind trial

Adverse event

Placebo arm

Nimotuzumab arm

Number of events

Number of events

Unrelated (Not related and unlikely)

Headache

42

17

Seizures

16

6

Dry radiodermitis

6

5

Fever

6

 

Asthenia

5

4

Liver function tests alterations

7

5

Alopecia

4

7

Possibly, probably or definitively related with nimotuzumab

Liver function tests alterations

 

8

Nauseas

 

4

Tremors

 

3

Anorexia

 

3

Fever

 

2