Figure 3
Effect of AG1478 or/and AG1024 plus irradiation on apoptosis in MDA-MB-468 and MCF-7 cells. Cells were exposed to DMSO in same concentration (as control), AG1478 10 μM, AG1024 10 μM or their combination combined with irradiation at dose of 4 Gy. Results are the mean value of three experiments, columns, mean; bars, S.D. (One-way ANOVAMDA-MB-468 F = 48.194, p < 0.001), ** p < 0.05, AG1478 + AG1024 + RT group vs. other treated groups. (a-b): Representative picture of the apoptosis on MDA-MB-468 (a) and MCF-7 (b) cells. (c-d) Graphs show the percentage of apoptosis on MDA-MB-468 (c) and MCF-7 (d) cells. RT = radiotherapy.