Skip to main content
Figure 2 | BMC Cancer

Figure 2

From: Co-inhibition of epidermal growth factor receptor and insulin-like growth factor receptor 1 enhances radiosensitivity in human breast cancer cells

Figure 2

Effect of AG1478 or/and AG1024 on radiosensitivity in MDA-MB-468 and MCF-7 cells. MDA-MB-468 and MCF-7 cells were treated with the following inhibitors: DMSO in same concentration (as control), 10 μM AG1478 (a, b), 10 μM AG1024 (c, d), or their combination (e, f) for 1 h. After irradiation with indicated dose for 48 h, cells were trypsinized, counted, seeded at different dilutions and incubated for 14 days. Vertical bars represent standard deviation. Points, mean values from three independent experiments. (One-way ANOVA MDA-MB-468, F = 4.568, p = 0.038 at dose of 10Gy). ** p < 0.05. AG1478 + AG1024 + RT group vs. Other treated groups. RT = radiotherapy.

Back to article page

BMC Cancer

ISSN: 1471-2407

Contact us