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Table 3 The relationship between patient characteristics and five and ten year relative survival and relative excess risk of death of patients with prostate cancer

From: The modified Glasgow prognostic score in prostate cancer: results from a retrospective clinical series of 744 patients

  Five year survival and excess risk of death P-value Ten year survival and excess risk of death P-value
  5-year relative survival Relative excess risk (95% CI) *   10-year relative survival Relative excess risk (95% CI)*  
Modified Glasgow prognostic score       
   0 74.8 (67.9-81.3) 1   51.4 (42.8-60.1) 1  
   1 48.3 (41.1-55.1) 1.84 (1.33-2.55) <0.001 22.4 (16.6-29.1) 1.87 (1.37-2.55) <0.001
   2 32.6 (19.8-47.3) 3.57 (2.31-5.52) <0.001 18.8 (7.6-36.1) 3.42 (2.25-5.21) <0.001
Age at incidence (years)       
   Age < 65 73.3 (65.1-80.2) 1   47.4 (37.6-56.9) 1  
   Age 65-74 58.4 (50.9-65.6) 1.69 (1.15-2.49) 0.008 36.1 (28.3-44.3) 1.49 (1.05-2.12) 0.026
   Age ≥ 75 51.6 (43.2-60.3) 1.92 (1.31-2.80) 0.001 24.4 (16.8-33.7) 1.69 (1.20-2.40) 0.003
Gleason score       
   Gleason < 7 96.6 (87.6-100) 1   68.9 (56.1-81.1) 1  
   Gleason = 7 77.0 (66.4-86.2) 2.96 (1.19-7.37) 0.020 44.3 (32.5-56.5) 2.74 (1.28-5.86) 0.010
   Gleason 8-10 50.0 (42.2-58.0) 7.18 (3.12-16.50) <0.001 25.1 (17.9-33.3) 5.55 (2.75-11.20) <0.001
   Unknown Gleason 16.3 (10.4-23.7) 16.27 (7.09-37.34) <0.001 7.5 (3.2-14.7) 12.44 (6.12-25.29) <0.001
SIMD 2006, Quintiles       
   1 (most deprived) 49.9 (42.8-56.9) 1   27.8 (20.9-35.5) 1  
   2 51.0 (40.9-61.1) 1.24 (0.88-1.73) 0.221 25.4 (16.5-36.0) 1.28 (0.92-1.78) 0.146
   3 70.4 (56.6-82.9) 0.80 (0.49-1.30) 0.364 35.2 (22.4-49.9) 0.91 (0.58-1.42) 0.682
   4 74.4 (59.2-87.9) 0.81 (0.48-1.36) 0.419 49.0 (32.1-67.3) 0.93 (0.58-1.49) 0.761
   5 (least deprived) 71.9 (59.4-83.6) 0.80 (0.51-1.24) 0.312 58.7 (42.2-76.2) 0.81 (0.53-1.23) 0.319
Prostate specific antigen (ug/l)       
   PSA < 10 78.0 (70.4-84.8) 1   58.2 (48.4-67.9) 1  
   PSA 10-20 73.1 (60.6-84.2) 0.78 (0.44-1.38) 0.396 45.4 (31.4-60.3) 0.78 (0.44-1.39) 0.409
   PSA > 20 40.4 (34.0-47.0) 1.47 (1.01-2.14) 0.041 15.4 (10.7-21.2) 1.82 (1.26-2.63) 0.002
Previous inpatient bed days      
   0 60.8 (54.5-66.9) 1   36.7 (30.3-44.0)   
   1-7 70.0 (59.2-79.9) 0.78 (0.53-1.15) 0.205 41.5 (29.7-54.2) 0.75 (0.51-1.09) 0.141
   8-28 52.7 (41.3-64.0) 1.07 (0.74-1.55) 0.708 26.3 (16.2-38.7) 1.12 (0.79-1.59) 0.530
   29+ 33.7 (19.7-49.5) 1.65 (1.09-2.51) 0.018 19.2 (7.1-38.6) 1.64 (1.08-2.47) 0.019
  1. *Multivariate model included all the co-variates presented in the table.
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