Table 3 The relationship between patient characteristics and five and ten year relative survival and relative excess risk of death of patients with prostate cancer
Five year survival and excess risk of death | P-value | Ten year survival and excess risk of death | P-value | |||
|---|---|---|---|---|---|---|
5-year relative survival | Relative excess risk (95% CI) * | 10-year relative survival | Relative excess risk (95% CI)* | |||
Modified Glasgow prognostic score | ||||||
0 | 74.8 (67.9-81.3) | 1 | 51.4 (42.8-60.1) | 1 | ||
1 | 48.3 (41.1-55.1) | 1.84 (1.33-2.55) | <0.001 | 22.4 (16.6-29.1) | 1.87 (1.37-2.55) | <0.001 |
2 | 32.6 (19.8-47.3) | 3.57 (2.31-5.52) | <0.001 | 18.8 (7.6-36.1) | 3.42 (2.25-5.21) | <0.001 |
Age at incidence (years) | ||||||
Age < 65 | 73.3 (65.1-80.2) | 1 | 47.4 (37.6-56.9) | 1 | ||
Age 65-74 | 58.4 (50.9-65.6) | 1.69 (1.15-2.49) | 0.008 | 36.1 (28.3-44.3) | 1.49 (1.05-2.12) | 0.026 |
Age ≥ 75 | 51.6 (43.2-60.3) | 1.92 (1.31-2.80) | 0.001 | 24.4 (16.8-33.7) | 1.69 (1.20-2.40) | 0.003 |
Gleason score | ||||||
Gleason < 7 | 96.6 (87.6-100) | 1 | 68.9 (56.1-81.1) | 1 | ||
Gleason = 7 | 77.0 (66.4-86.2) | 2.96 (1.19-7.37) | 0.020 | 44.3 (32.5-56.5) | 2.74 (1.28-5.86) | 0.010 |
Gleason 8-10 | 50.0 (42.2-58.0) | 7.18 (3.12-16.50) | <0.001 | 25.1 (17.9-33.3) | 5.55 (2.75-11.20) | <0.001 |
Unknown Gleason | 16.3 (10.4-23.7) | 16.27 (7.09-37.34) | <0.001 | 7.5 (3.2-14.7) | 12.44 (6.12-25.29) | <0.001 |
SIMD 2006, Quintiles | ||||||
1 (most deprived) | 49.9 (42.8-56.9) | 1 | 27.8 (20.9-35.5) | 1 | ||
2 | 51.0 (40.9-61.1) | 1.24 (0.88-1.73) | 0.221 | 25.4 (16.5-36.0) | 1.28 (0.92-1.78) | 0.146 |
3 | 70.4 (56.6-82.9) | 0.80 (0.49-1.30) | 0.364 | 35.2 (22.4-49.9) | 0.91 (0.58-1.42) | 0.682 |
4 | 74.4 (59.2-87.9) | 0.81 (0.48-1.36) | 0.419 | 49.0 (32.1-67.3) | 0.93 (0.58-1.49) | 0.761 |
5 (least deprived) | 71.9 (59.4-83.6) | 0.80 (0.51-1.24) | 0.312 | 58.7 (42.2-76.2) | 0.81 (0.53-1.23) | 0.319 |
Prostate specific antigen (ug/l) | ||||||
PSA < 10 | 78.0 (70.4-84.8) | 1 | 58.2 (48.4-67.9) | 1 | ||
PSA 10-20 | 73.1 (60.6-84.2) | 0.78 (0.44-1.38) | 0.396 | 45.4 (31.4-60.3) | 0.78 (0.44-1.39) | 0.409 |
PSA > 20 | 40.4 (34.0-47.0) | 1.47 (1.01-2.14) | 0.041 | 15.4 (10.7-21.2) | 1.82 (1.26-2.63) | 0.002 |
Previous inpatient bed days | ||||||
0 | 60.8 (54.5-66.9) | 1 | 36.7 (30.3-44.0) | |||
1-7 | 70.0 (59.2-79.9) | 0.78 (0.53-1.15) | 0.205 | 41.5 (29.7-54.2) | 0.75 (0.51-1.09) | 0.141 |
8-28 | 52.7 (41.3-64.0) | 1.07 (0.74-1.55) | 0.708 | 26.3 (16.2-38.7) | 1.12 (0.79-1.59) | 0.530 |
29+ | 33.7 (19.7-49.5) | 1.65 (1.09-2.51) | 0.018 | 19.2 (7.1-38.6) | 1.64 (1.08-2.47) | 0.019 |