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Table 2 Relative risks for shorter progression-free survival (PFS) and overall survival (OS) estimated with Cox proportional hazard models

From: ID3 contributes to cerebrospinal fluid seeding and poor prognosis in medulloblastoma

  Crude HR 95% Hazard ratio confidence interval Adjusted HR 95% Hazard ratio confidence interval
PFS       
Sex 1.383 0.571 3.349 0.745 0.276 2.012
Age at diagnosis (<3 yrs) 2.558 0.989 6.617 4.612 1.527 13.927
Residual tumor (> 1.5 cm2) 27.303 4.299 173.409 5.990 0.681 52.719
Seeding at presentation 3.871 1.663 9.008 3.546 1.142 11.014
Anaplastic histology 3.254 1.086 9.748 8.229 1.465 46.242
High ID3 expression 2.018 0.887 4.595 2.137 0.684 6.676
OS       
Sex 2.043 0.747 5.585 1.286 0.428 3.863
Age at diagnosis (<3 yrs) 2.195 0.780 6.179 4.323 1.249 14.959
Residual tumor (> 1.5 cm2) 4.374 1.225 15.619 0.680 0.120 3.834
Seeding at presentation 4.734 1.881 11.914 3.373 1.113 10.222
Anaplastic histology 3.200 1.056 9.691 13.235 2.058 85.090
High ID3 expression 2.609 1.090 6.249 3.840 1.107 13.312