Table 2 Relative risks for shorter progression-free survival (PFS) and overall survival (OS) estimated with Cox proportional hazard models
From: ID3 contributes to cerebrospinal fluid seeding and poor prognosis in medulloblastoma
Crude HR | 95% Hazard ratio confidence interval | Adjusted HR | 95% Hazard ratio confidence interval | |||
|---|---|---|---|---|---|---|
PFS | ||||||
Sex | 1.383 | 0.571 | 3.349 | 0.745 | 0.276 | 2.012 |
Age at diagnosis (<3 yrs) | 2.558 | 0.989 | 6.617 | 4.612 | 1.527 | 13.927 |
Residual tumor (> 1.5 cm2) | 27.303 | 4.299 | 173.409 | 5.990 | 0.681 | 52.719 |
Seeding at presentation | 3.871 | 1.663 | 9.008 | 3.546 | 1.142 | 11.014 |
Anaplastic histology | 3.254 | 1.086 | 9.748 | 8.229 | 1.465 | 46.242 |
High ID3 expression | 2.018 | 0.887 | 4.595 | 2.137 | 0.684 | 6.676 |
OS | ||||||
Sex | 2.043 | 0.747 | 5.585 | 1.286 | 0.428 | 3.863 |
Age at diagnosis (<3 yrs) | 2.195 | 0.780 | 6.179 | 4.323 | 1.249 | 14.959 |
Residual tumor (> 1.5 cm2) | 4.374 | 1.225 | 15.619 | 0.680 | 0.120 | 3.834 |
Seeding at presentation | 4.734 | 1.881 | 11.914 | 3.373 | 1.113 | 10.222 |
Anaplastic histology | 3.200 | 1.056 | 9.691 | 13.235 | 2.058 | 85.090 |
High ID3 expression | 2.609 | 1.090 | 6.249 | 3.840 | 1.107 | 13.312 |