Skip to main content

Table 3 Characterization of Ep-CAM/CD49f populations and the stem/progenitor cell markers they express

From: Profiling of normal and malignant breast tissue show CD44high/CD24lowphenotype as a predominant stem/progenitor marker when used in combination with Ep-CAM/CD49f markers

Population Lineage Mammosphere formation Has colony forming cells Expressed "stem cell" markers
ALDH CD10 CD44high/CD24low Ep-CAM+/MUC-1neg
Ep-CAMneg/CD49fneg Mesenchymal +++ ++ +++ -
Ep-CAMhigh/CD49fneg Luminal NO NO - - + +
Ep-CAMhigh/CD49f+ Luminal +++ - + +++
Ep-CAMlow/CD49f+ Myoepithelial - +++ ++ ++