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Figure 5 | BMC Cancer

Figure 5

From: The histone deacetylase inhibitor SAHA acts in synergism with fenretinide and doxorubicin to control growth of rhabdoid tumor cells

Figure 5

HDACi and fenretinide act synergistic on induction of apoptosis. A204 cells were treated for 72 h with HDACi SAHA (1 μM, 10 μM), fenretinide (4HPR) (1 μM, 10 μM) or combinations of both compounds. Low concentrations (1 μM) of SAHA (B) or fenretinide (C) as single treatment do not induce apoptosis compared to control (A). High concentrations (10 μM) of SAHA (D) or high concentrations of fenretinide (E), as well as low concentrations of combined treatment of SAHA plus fenretinide, induce apoptosis (F).

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BMC Cancer

ISSN: 1471-2407

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